US 11,911,278 B2
Implant materials for TMJ repair, methods of making the implant materials for TMJ repair, and method of using implant materials for TMJ repair
Peter S. McFetridge, Gainesville, FL (US)
Assigned to University of Florida Research Foundation, Inc., Gainesville, FL (US)
Filed by University of Florida Research Foundation, Inc., Gainesville, FL (US)
Filed on Sep. 25, 2020, as Appl. No. 17/032,402.
Application 17/032,402 is a division of application No. 14/363,538, granted, now 10,828,165, previously published as PCT/US2012/068385, filed on Dec. 7, 2012.
Claims priority of provisional application 61/568,733, filed on Dec. 9, 2011.
Prior Publication US 2021/0007850 A1, Jan. 14, 2021
Int. Cl. A61F 2/30 (2006.01); A61L 27/38 (2006.01); A61L 27/36 (2006.01)
CPC A61F 2/3099 (2013.01) [A61L 27/3612 (2013.01); A61L 27/3662 (2013.01); A61L 27/3687 (2013.01); A61L 27/3691 (2013.01); A61L 27/38 (2013.01); A61L 27/386 (2013.01); A61L 27/3834 (2013.01); A61L 27/3886 (2013.01); A61F 2002/30754 (2013.01); A61L 2430/10 (2013.01); A61L 2430/24 (2013.01); A61L 2430/40 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A temporomandibular joint (TMJ) disc, comprising:
a TMJ scaffold structure comprising a freeze-dried, decellularized fibrocartilage tissue from a subject animal, the TMJ scaffold structure having a plurality of drilled holes in the scaffold structure,
wherein the TMJ scaffold structure is obtained from a precursor TMJ scaffold structure comprising said fibrocartilage tissue from a subject animal,
wherein the freeze-dried, decellularized fibrocartilage tissue has a compressive modulus and a peak stress value less than that of a corresponding sodium dodecyl sulfate (SDS) decellularized fibrocartilage tissue that has never been freeze-dried.