US 11,911,173 B2
Preclinical evaluation of skin condition and risk evaluation
Paul Blount, Derbyshire (GB); John Hines, Derbyshire (GB); Caroline Fellows, Derbyshire (GB); Chris Lang, Derbyshire (GB); Chris Mann, Derbyshire (GB); and Kevin Ormandy, Derbyshire (GB)
Assigned to Deb IP Limited, Derbyshire (GB)
Appl. No. 16/649,958
Filed by DEB IP LIMITED, Derbyshire (GB)
PCT Filed Sep. 14, 2018, PCT No. PCT/GB2018/052619
§ 371(c)(1), (2) Date Mar. 23, 2020,
PCT Pub. No. WO2019/058100, PCT Pub. Date Mar. 28, 2019.
Claims priority of application No. 1715447 (GB), filed on Sep. 25, 2017.
Prior Publication US 2020/0221993 A1, Jul. 16, 2020
Int. Cl. A61B 5/00 (2006.01); G16H 50/30 (2018.01); A61B 5/01 (2006.01)
CPC A61B 5/445 (2013.01) [A61B 5/0064 (2013.01); A61B 5/015 (2013.01); A61B 5/442 (2013.01); A61B 5/443 (2013.01); A61B 5/7275 (2013.01); G16H 50/30 (2018.01); A61B 2503/20 (2013.01); A61B 2562/029 (2013.01); A61B 2562/0233 (2013.01); A61B 2562/0271 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A system configured to quantify risk associated with preclinical indicators of one or more hand based clinical skin conditions,
the system comprising a plurality of measurement tools in connection with a processor, each of the plurality of measurement tools configured to measure at least one property of the skin of a subject's hand, said property related to skin health, wherein the measurement tools are configured to measure at least two properties, comprising at least two of erythema, scaling, papule density, vesicle density, infiltration, fissuring, skin barrier function, surface hydration level, or transepidermal water loss of the subject's hand, provided that the at least two properties do not comprise the surface hydration level and the transepidermal water loss of the subject's hand,
wherein each of the plurality of measurement tools is configured to provide a respective first score, wherein each first score corresponds to a respective property,
wherein each of the plurality of first scores are normalized with respect to each other,
wherein the processor is configured to calculate a second score based on the plurality of first scores, the second score representing the subject's risk of future development of one or more clinical skin conditions,
wherein the system calculates a plurality of the second scores for a number of multiple subjects, wherein the number the multiple subjects comprise a statistically significant sample of a population within a work site, and
wherein the processor is configured to determine a third score based on the plurality of the second scores to quantify risk associated with preclinical indicators of one or more hand-based clinical skin conditions for the work site.