US 11,911,107 B2
System, method and apparatus for retinal absorption phase and dark field imaging with oblique illumination
Timothé Laforest, Sivignon (FR); Dino Carpentras, Ecublens (CH); Christophe Moser, Lausanne (CH); Mathieu Künzi, Chêne-Bourg (CH); and Francine Behar-Cohen, Paris (FR)
Assigned to ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL), Lausanne (CH)
Filed by ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL), Lausanne (CH)
Filed on Oct. 29, 2021, as Appl. No. 17/514,604.
Application 17/514,604 is a continuation of application No. 16/300,937, granted, now 11,179,033, previously published as PCT/IB2017/052803, filed on May 12, 2017.
Prior Publication US 2022/0117485 A1, Apr. 21, 2022
Int. Cl. A61B 3/12 (2006.01); A61B 3/00 (2006.01); A61B 3/14 (2006.01)
CPC A61B 3/12 (2013.01) [A61B 3/0008 (2013.01); A61B 3/14 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method for imaging a tissue of an eye, the method comprising the steps of:
providing oblique illumination to the eye by a plurality of light emitting areas of a light delivery device, the plurality of light emitting areas being independently controllable and arranged to direct light towards at least one of a retina and an iris of the eye;
causing an output beam from light backscattered from the at least one of the retina and the iris by the oblique illumination;
capturing the output beam with an imaging system to provide a sequence of images of a fundus of the eye; and
retrieving a phase and absorption contrast image from the sequence of images of the fundus,
wherein the sequence of images of the fundus of the step of capturing is obtained by sequentially turning on one or more of the plurality of light emitting areas at a time in the step of providing the oblique illumination.