transmitting, by a base station to a wireless device, one or more messages comprising one or more configuration parameters comprising a pathloss reference signal update parameter that enables an activation command to update pathloss reference signals of a physical uplink shared channel (PUSCH); and

receiving, from the wireless device and based on the one or more configuration parameters comprising the pathloss reference signal update parameter, a power headroom report computed based on a pathloss estimation of a pathloss reference signal associated with a PUSCH pathloss reference signal identifier mapped to a sounding reference signal resource indicator (SRI)-PUSCH power control parameter set with an index equal to zero.