| CPC G06T 7/0012 (2013.01) [G06F 18/211 (2023.01); G06F 18/2148 (2023.01); G06F 18/24 (2023.01); G06N 3/08 (2013.01); G06N 20/00 (2019.01); G06T 3/00 (2013.01); G06T 5/73 (2024.01); G06T 7/11 (2017.01); G06V 10/25 (2022.01); G06V 10/764 (2022.01); G06V 20/69 (2022.01); G06T 2207/10048 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/10088 (2013.01); G06T 2207/10101 (2013.01); G06T 2207/10104 (2013.01); G06T 2207/10108 (2013.01); G06T 2207/10132 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/30096 (2013.01); G06T 2207/30104 (2013.01)] | 12 Claims |

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1. A system for implementing a layered analytics framework, the system comprising:
a processor configured to:
receive imaging data of Computed Tomography (CT), Magnetic resonance (MR), Ultrasound (US), or Positron Emission Tomography (PET) of a patient, imaged at two or more points in time;
for each of the points in time, determine, based on the received imaging data at each respective point in time, a set of segmentations including lumen, wall, or a combination thereof, wherein the set of segmentation includes one or more cross sectional slices of a vessel;
determine, based on the set of segmentations, a change in a set of quantities that identify or characterize permeability, neovascularization, necrosis, collagen breakdown, or inflammation, across the points in time; and
output the identification or characterization of the permeability, neovascularization, necrosis, collagen breakdown, or inflammation for each of the points in time.
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