US 12,234,499 B2
Compositions, methods, systems and/or kits for detecting antimicrobial resistance in bacteria
William B. Brasso, Columbia, MD (US); David J. Turner, York, PA (US); Susan M. Kircher, Hanover, PA (US); and Fatimah Alrashidi-Brooks, Franklin Lakes, NJ (US)
Assigned to BECTON, DICKINSON AND COMPANY, Franklin Lakes, NJ (US)
Filed by BECTON, DICKINSON AND COMPANY, Franklin Lakes, NJ (US)
Filed on Mar. 25, 2022, as Appl. No. 17/705,153.
Application 17/705,153 is a division of application No. 16/313,846, granted, now 11,286,512, previously published as PCT/US2017/039305, filed on Jun. 26, 2017.
Claims priority of provisional application 62/466,987, filed on Mar. 3, 2017.
Claims priority of provisional application 62/443,590, filed on Jan. 6, 2017.
Claims priority of provisional application 62/355,169, filed on Jun. 27, 2016.
Prior Publication US 2022/0380830 A1, Dec. 1, 2022
Int. Cl. C12Q 1/18 (2006.01); C12Q 1/10 (2006.01); C12Q 1/34 (2006.01)
CPC C12Q 1/18 (2013.01) [C12Q 1/10 (2013.01); C12Q 1/34 (2013.01); G01N 2333/986 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A kit for determining the presence of none, one or more Ambler class carbapenemases expressed by enteric bacteria, the kit comprising:
a plurality of compartments, wherein:
a first compartment of the plurality of compartments comprises a first test composition, wherein the antibiotic and inhibitor comprise a first concentration of temocillin (TEM), and a carbapenemase inhibitor of ambler class B;
a second compartment of the plurality of compartments comprises a second test composition, wherein the antibiotic and inhibitors comprise a first concentration of doripenem (DOR), a carbapenemase inhibitor of ambler class C, and a carbapenemase inhibitor of ambler class B;
a third compartment of the plurality of compartments comprises a third test composition, wherein the antibiotic and inhibitors comprise a first concentration of meropenem (MEM), a carbapenemase inhibitor of ambler class C, and a carbapenemase inhibitor of ambler class A; and
a fourth compartment of the plurality of compartments comprises a fourth test composition, wherein the antibiotic comprises a second concentration of DOR.