	US 12,234,473 B2
	CD8 polypeptides, compositions, and methods of using thereof
Gagan Bajwa, Houston, TX (US); Mamta Kalra, Houston, TX (US); and Melinda Mata, Missouri City, TX (US)
Assigned to Immatics US, INC., Stafford, TX (US)
Filed by Immatics US, Inc., Houston, TX (US)
Filed on Dec. 28, 2021, as Appl. No. 17/563,599.
Claims priority of provisional application 63/247,775, filed on Sep. 23, 2021.
Claims priority of provisional application 63/132,824, filed on Dec. 31, 2020.
Claims priority of application No. 102021100038.6 (DE), filed on Jan. 4, 2021.
Prior Publication US 2022/0202862 A1, Jun. 30, 2022
Int. Cl. A61K 35/17 (2015.01); A61K 39/00 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C12N 5/0783 (2010.01); C12N 15/86 (2006.01)

CPC C12N 15/86 (2013.01) [A61K 39/4611 (2023.05); A61K 39/4632 (2023.05); A61K 39/464411 (2023.05); A61K 39/464489 (2023.05); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C12N 5/0636 (2013.01); C12N 2810/55 (2013.01)]

12 Claims

1. A nucleic acid encoding a T-cell receptor (TCR) comprising an α chain and a β chain and a CD8 α chain,

wherein the CD8 α chain comprises the amino acid sequence with at least 98% identity to SEQ ID NO: 5.