US 12,234,302 B2
Chitosan derivatives and methods for preparing the same
Mar Masson, Reykjavik (IS)
Assigned to PRIMEX EHF, Fjallabyggd (IS)
Filed by Primex ehf., Fjallabyggð (IS)
Filed on Nov. 22, 2022, as Appl. No. 18/057,825.
Application 18/057,825 is a division of application No. 17/270,237, granted, now 11,535,684, previously published as PCT/IS2019/050009, filed on Aug. 23, 2019.
Claims priority of application No. 050236 (IS), filed on Aug. 23, 2018.
Prior Publication US 2023/0151121 A1, May 18, 2023
Int. Cl. C08B 37/08 (2006.01); A61K 31/722 (2006.01)
CPC C08B 37/003 (2013.01) [A61K 31/722 (2013.01)] 5 Claims
 
1. A compound having the formula

OG Complex Work Unit Chemistry
wherein n is an integer greater than or equal to 3,
wherein W is N-acetyl:

OG Complex Work Unit Chemistry
in from 0 to 70% of monomer units and where W is not N-acetyl it is a group selected from:

OG Complex Work Unit Chemistry
wherein each R1 substituent is independently selected from H, CH3, and —(CH2)a—CH3,
wherein a is from 1 to 22, provided that when R1 is present it is not H in at least 10% of monomer units, and
wherein R2 is selected from:

OG Complex Work Unit Chemistry
wherein i is an integer from 1-200, and R3 is selected from H, —(CH2)j—CH3 and —CO—(CH2)j—CH3, wherein j is 0, 1, 2, 3, 4, or 5,
wherein R is H in at least 75% of the total number of positions, and when it is not H, R is the same as amino substituent R1 or R2 in W;
or a salt thereof.