US 12,234,299 B2
Peptides for inducing bacteriocin synthesis and methods to identify and/or select and/or optimize the same
Johann Mignolet, Saint-Gérard (BE); Pascal Hols, Vedrin (BE); and Laura Ledesma García, Ixelles (BE)
Assigned to SYNGULON S.A., Seraing (BE); and Université catholique de Louvain, Louvain-la-Neuve (BE)
Appl. No. 17/309,375
Filed by SYNGULON S.A., Seraing (BE); and Université catholique de Louvain, Louvain-la-neuve (BE)
PCT Filed Nov. 22, 2019, PCT No. PCT/EP2019/082242
§ 371(c)(1), (2) Date May 21, 2021,
PCT Pub. No. WO2020/104662, PCT Pub. Date May 28, 2020.
Claims priority of application No. 18207694 (EP), filed on Nov. 22, 2018.
Prior Publication US 2022/0017573 A1, Jan. 20, 2022
Int. Cl. C07K 7/06 (2006.01); C07K 1/06 (2006.01); C07K 14/195 (2006.01)
CPC C07K 7/06 (2013.01) [C07K 14/195 (2013.01); C07K 1/061 (2013.01)] 14 Claims
 
1. A peptide able to induce bacteriocin production in a microbial organism with a length of at least 6 residues, comprising a sequences motif selected from:
Phe-Trp-Leu-Val-Leu-Gly (SEQ ID NO: 2);
Ala-Phe-Trp-Leu-Ile-Leu-Gly (SEQ ID NO: 3); and
Pro-Phe-Trp-Leu-Ile-Leu-Gly (SEQ ID NO: 7),
wherein the sequence motif is located at the C-terminus of said peptide or located so that it is followed by at most 1, 2, 3, 4 or 5 additional C-terminal residues.