US 12,234,269 B2
Osteogenic biomaterial
Fayez Safadi, Akron, OH (US)
Assigned to Northeast Ohio Medical University, Rootstown, OH (US)
Filed by Northeast Ohio Medical University, Rootstown, OH (US)
Filed on Jun. 7, 2021, as Appl. No. 17/340,405.
Application 17/340,405 is a continuation of application No. 15/512,964, granted, now 11,028,140, previously published as PCT/US2015/051349, filed on Sep. 22, 2015.
Claims priority of provisional application 62/053,445, filed on Sep. 22, 2014.
Prior Publication US 2021/0300980 A1, Sep. 30, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/00 (2006.01); A61K 31/00 (2006.01); A61K 38/17 (2006.01); A61K 47/36 (2006.01); A61L 24/00 (2006.01); A61L 27/24 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); A61P 19/00 (2006.01); C07K 14/51 (2006.01); A61F 2/30 (2006.01); A61K 47/34 (2017.01)
CPC C07K 14/51 (2013.01) [A61K 9/0024 (2013.01); A61K 38/1709 (2013.01); A61K 47/36 (2013.01); A61L 24/0015 (2013.01); A61L 24/0042 (2013.01); A61L 27/24 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61L 31/148 (2013.01); A61L 31/16 (2013.01); A61F 2002/30062 (2013.01); A61K 31/00 (2013.01); A61K 47/34 (2013.01); A61L 2300/25 (2013.01); A61L 2300/412 (2013.01); A61L 2430/02 (2013.01); C07K 2319/00 (2013.01)] 11 Claims
 
1. A composition for enhancing bone tissue repair or regeneration, comprising a therapeutically effective amount of an active peptide fragment of osteoactivin having the amino acid sequence of SEQ ID NO: 1 and a biocompatible inorganic material configured as a tissue scaffold.