US 12,234,237 B2
Folate salts
Martin Ulmann, Dachsen (CH); Gerd Wiesler, Lohn (CH); Arthur Bodenmüller, Seltisberg (CH); and Markus Müller
Assigned to APROFOL AG, (CH)
Filed by APROFOL AG, Appenzell Steinegg (CH)
Filed on Sep. 8, 2023, as Appl. No. 18/243,991.
Application 18/243,991 is a continuation of application No. 17/289,609, granted, now 11,787,808, previously published as PCT/EP2019/079941, filed on Oct. 31, 2019.
Claims priority of application No. 18203849 (EP), filed on Oct. 31, 2018.
Prior Publication US 2023/0416253 A1, Dec. 28, 2023
Int. Cl. A61K 31/519 (2006.01); A23L 33/10 (2016.01); C07D 475/04 (2006.01)
CPC C07D 475/04 (2013.01) [A23L 33/10 (2016.08); A61K 31/519 (2013.01); C07B 2200/13 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A crystalline folate salt comprising a tetrahydrofolic acid anion and an organic cation where the anion is 5-methyl-(6S)-tetrahydrofolic acid, and the cation is an organic compound wherein the organic compound is an alkanolamine selected from the group consisting of 2-dimethylaminoethanol, N-methylaminoethanol, and 2-amino-2methylpropanol.