US 12,233,634 B2
Porous body and material for medical use
Yasumoto Nakazawa, Tokyo (JP); Chiemi Sakata, Tokyo (JP); Shuhei Tara, Tokyo (JP); and Eri Koyanagi, Tokyo (JP)
Assigned to National University Corporation Tokyo University of Agriculture and Technology, Tokyo (JP); and NIPPON MEDICAL SCHOOL FOUNDATION, Tokyo (JP)
Appl. No. 16/972,603
Filed by National University Corporation Tokyo University of Agriculture and Technology, Tokyo (JP); and NIPPON MEDICAL SCHOOL FOUNDATION, Tokyo (JP)
PCT Filed Jun. 5, 2019, PCT No. PCT/JP2019/022418
§ 371(c)(1), (2) Date Dec. 6, 2020,
PCT Pub. No. WO2019/235543, PCT Pub. Date Dec. 12, 2019.
Claims priority of application No. 2018-108148 (JP), filed on Jun. 5, 2018.
Prior Publication US 2021/0299333 A1, Sep. 30, 2021
Int. Cl. B32B 5/08 (2006.01); B32B 5/26 (2006.01); B32B 7/02 (2019.01); A61F 2/82 (2013.01); A61L 27/26 (2006.01); A61L 27/50 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01)
CPC B32B 5/08 (2013.01) [B32B 5/266 (2021.05); B32B 5/271 (2021.05); B32B 7/02 (2013.01); A61F 2/82 (2013.01); A61L 27/26 (2013.01); A61L 27/507 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); B32B 2250/20 (2013.01); B32B 2262/0292 (2013.01); B32B 2262/08 (2013.01); B32B 2262/124 (2021.05); B32B 2307/54 (2013.01); B32B 2307/7163 (2013.01); B32B 2535/00 (2013.01); Y10T 428/1352 (2015.01); Y10T 428/1376 (2015.01)] 16 Claims
OG exemplary drawing
 
1. A porous body which has a first surface and a second surface, and which comprises a first polymer material and a second polymer material, wherein
a Young's modulus of the first polymer material is lower than a Young's modulus of the second polymer material,
absorbability of the first polymer material with respect to phosphate buffered saline is greater than absorbability of the second polymer material with respect to phosphate buffered saline,
a composition of the porous body in a first region and a composition of the porous body in a second region are different from each other,
a distance between the first region and the first surface is shorter than a distance between the second region and the first surface, and
the second polymer material comprises at least one selected from a group consisting of (i) chitin, sericin, fibroin, carboxymethyl cellulose, and chitosan, and (ii) salts and derivatives of these.