	US 12,233,412 B2
	Disposable fluidic cartridge and components
Robert Turner, San Diego, CA (US); James Madsen, San Diego, CA (US); Kai Yang, San Diego, CA (US); Juan Pablo Hinestrosa Salazar, San Diego, CA (US); Rajaram Krishnan, San Diego, CA (US); and Pedro David Simon Herrera, San Diego, CA (US)
Assigned to Xzom, Inc., San Diego, CA (US)
Filed by Xzom, Inc., San Diego, CA (US)
Filed on Dec. 15, 2022, as Appl. No. 18/066,803.
Application 18/066,803 is a continuation of application No. 16/355,462, filed on Mar. 15, 2019, granted, now 11,534,756.
Application 16/355,462 is a continuation of application No. 15/469,406, filed on Mar. 24, 2017, granted, now 10,232,369, issued on Mar. 19, 2019.
Claims priority of provisional application 62/313,120, filed on Mar. 24, 2016.
Prior Publication US 2023/0182132 A1, Jun. 15, 2023
Int. Cl. B01L 3/00 (2006.01)

CPC B01L 3/502715 (2013.01) [B01L 3/5027 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/16 (2013.01); B01L 2300/023 (2013.01); B01L 2300/027 (2013.01); B01L 2300/041 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/165 (2013.01); B01L 2300/168 (2013.01); B01L 2400/0424 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0638 (2013.01); B01L 2400/0694 (2013.01)]

19 Claims

1. A compact device for isolating nanoscale analytes in a sample, the compact device comprising:

(a) a housing (101) comprising an optical pathway (106), wherein the housing is configured to receive a fluidic cartridge (104) comprising:

(i) a fluid moving mechanism (213), wherein the fluid moving mechanism draws fluid through the fluidic cartridge; and

(ii) a flowcell (209); and

(b) a camera (120) configured to capture a signal generated in the flowcell by the isolated nanoscale analytes,

wherein the fluidic cartridge comprises an electronic chip comprising a plurality of alternating current (AC) electrodes configured to capture the nanoscale analytes, wherein the optical pathway and the fluidic cartridge are optically transparent, and wherein the signal is indicative of the presence or absence of disease.