US 12,233,411 B2
Detection chip, method of using detection chip and reaction system
Ruijun Deng, Beijing (CN); Mengjun Hou, Beijing (CN); Zhukai Liu, Beijing (CN); and Jing Yu, Beijing (CN)
Assigned to BOE TECHNOLOGY GROUP CO., LTD., Beijing (CN)
Appl. No. 17/430,854
Filed by BOE TECHNOLOGY GROUP CO., LTD., Beijing (CN)
PCT Filed Mar. 12, 2021, PCT No. PCT/CN2021/080523
§ 371(c)(1), (2) Date Aug. 13, 2021,
PCT Pub. No. WO2021/218450, PCT Pub. Date Nov. 4, 2021.
Claims priority of application No. 202010367934.4 (CN), filed on Apr. 30, 2020.
Prior Publication US 2022/0410149 A1, Dec. 29, 2022
Int. Cl. B01L 3/00 (2006.01); A61L 27/16 (2006.01); A61L 27/56 (2006.01); B01F 23/00 (2022.01); B01F 23/41 (2022.01); B01F 101/23 (2022.01); B01L 7/00 (2006.01); B01L 9/00 (2006.01); B23Q 17/24 (2006.01); C07K 14/705 (2006.01); C08F 220/56 (2006.01); C08L 33/26 (2006.01); C12M 1/34 (2006.01); C12Q 1/04 (2006.01); C12Q 1/18 (2006.01); C12Q 1/686 (2018.01); G01N 1/31 (2006.01); G01N 21/17 (2006.01); G01N 21/3577 (2014.01); G01N 21/359 (2014.01); G01N 21/39 (2006.01); G01N 21/45 (2006.01); G01N 21/64 (2006.01); G01N 21/77 (2006.01); G01N 21/78 (2006.01); G01N 27/414 (2006.01); G01N 30/12 (2006.01); G01N 30/68 (2006.01); G01N 30/70 (2006.01); G01N 30/72 (2006.01); G01N 30/88 (2006.01); G01N 33/00 (2006.01); G01N 33/18 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01); G01N 35/00 (2006.01); G01N 35/10 (2006.01); G06T 7/00 (2017.01); G06T 7/90 (2017.01); H10K 10/46 (2023.01); H10K 85/00 (2023.01); H10K 85/20 (2023.01)
CPC B01L 3/502715 (2013.01) [B01L 7/52 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/161 (2013.01); B01L 2300/1827 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A detection chip, comprising:
a first substrate;
a micro-chamber definition layer, located on the first substrate and defining a plurality of micro-reaction chambers;
a heating electrode, located on the first substrate and closer to the first substrate than the micro-chamber definition layer, configured to release heat after being energized;
wherein the heating electrode comprises a plurality of sub-electrodes, orthographic projections of the plurality of micro-reaction chambers on the first substrate overlap with orthographic projections of at least two of the plurality of sub-electrodes on the first substrate, and the at least two of the plurality of sub-electrodes have different heating values per unit time after being energized,
wherein the heating electrode is configured to allow a current to flow along a first direction after being energized, and the plurality of sub-electrodes are arranged at intervals along a second direction, and the second direction is perpendicular to the first direction,
each of the plurality of sub-electrodes has two sides opposite to each other in the second direction, and the plurality of sub-electrodes comprise a first sub-electrode and at least one second sub-electrode, wherein the first sub-electrode has adjacent sub-electrode on only one of the two sides, and each of the at least one second sub-electrode has adjacent sub-electrodes on the two sides, and
a resistance value of the second sub-electrode is larger than a resistance value of the first sub-electrode.