US 12,233,279 B2
Device for photo-therapy and use thereof
William Woodburn, Greenwich, CT (US)
Assigned to Icahn School of Medicine at Mount Sinai, Greenwich, CT (US)
Filed by Tcellerate LLC, Stamford, CT (US)
Filed on Dec. 30, 2021, as Appl. No. 17/646,613.
Application 17/646,613 is a continuation in part of application No. 16/168,768, filed on Oct. 23, 2018, granted, now 11,273,320.
Application 16/168,768 is a continuation in part of application No. 15/608,588, filed on May 30, 2017, granted, now 10,155,122, issued on Dec. 18, 2018.
Prior Publication US 2022/0118276 A1, Apr. 21, 2022
Int. Cl. A61N 5/06 (2006.01)
CPC A61N 5/0613 (2013.01) [A61N 2005/0651 (2013.01); A61N 2005/0654 (2013.01); A61N 2005/0663 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A method for treating an internal medical condition affected by a subject's immune system response involving T cells, the method comprising:
applying blue LED light radiation to exposed skin surfaces of the subject,
wherein the blue LED light radiation is uniformly applied to the exposed skin surfaces of at least the subject's upper torso including both front and back sides by a plurality of blue LED light generating lamps each having a wattage of at least about 15 watts for a total exposure time of at least about 10 minutes per each of the both front and back sides, with the emitted blue light having a wavelength in the range of between about 410 and 490 nm, so that at least about 250 watts-minute of the blue LED light radiation is applied to the subject.
 
13. A method for activating T cells in a subject in need thereof, comprising:
applying blue LED light radiation to exposed skin surfaces of the subject,
wherein the blue LED light radiation is uniformly applied to the exposed skin surfaces of at least the subject's upper torso including both front and back sides by a plurality of blue LED light generating lamps each having a wattage of at least about 15 watts for a total exposure time of at least about 10 minutes per each of the both front and back sides, with the emitted blue light having a wavelength in the range of between about 410 and 490 nm, so that at least about 250 watts-minute of the blue LED light radiation is applied to the subject, and
wherein a serum concentration of a T cell marker increases in the subject after applying the radiation.