| CPC A61N 1/36585 (2013.01) [A61N 1/3624 (2013.01); A61N 1/36578 (2013.01); A61N 1/368 (2013.01); A61N 1/3706 (2013.01); A61N 1/3937 (2013.01); A61N 1/3956 (2013.01)] | 13 Claims |

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1. An implantable medical device comprising:
a plurality of electrodes comprising:
a first electrode configured to be implanted in an atrium of a patient's heart to deliver cardiac therapy or sense electrical activity of the atrium of the patient's heart; and
a second electrode configured to be implanted in a septal wall of the patient's heart distal to the first electrode and to deliver cardiac therapy to or sense electrical activity of a ventricle of the patient's heart;
a motion detector configured to detect mechanical activity of the patient's heart;
a therapy delivery circuit operably coupled to the plurality of electrodes;
a sensing circuit operably coupled to the plurality of electrodes and the motion detector; and
a controller comprising processing circuitry operably coupled to the therapy delivery circuit and the sensing circuit, the controller configured to:
initiate the delivery of the cardiac therapy to the patient's heart using the therapy delivery circuit, the sensing circuit, and the plurality of electrodes;
detect the electrical activity of the ventricle of the patient's heart during a plurality of cardiac cycles using the second electrode over a period of time;
determine a plurality of ventricular activations based on the detected electrical activity of the ventricle of the patient's heart;
detect the mechanical activity of the patient's heart using the motion detector over the period of time;
determine a plurality of ventricular contractions based on the detected mechanical activity of the patient's heart;
determine an electromechanical interval for each of the cardiac cycles over the period of time based on the determined ventricular activation and the determined ventricular contraction within the cardiac cycle resulting in a plurality of electromechanical intervals; and
determine whether the patient's heart is experiencing effective ventricular remodeling in response to the cardiac therapy based on the plurality of electromechanical intervals.
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