US 12,233,186 B2
Fluoropolymer based anti-thrombotic coatings
Saibal Bandyopadhyay, Lancaster, PA (US); and Andrew K. Jones, Lancaster, PA (US)
Assigned to Cerulean Scientific Inc., Durham, NC (US)
Filed by CERULEAN SCIENTIFIC INC., Durham, NC (US)
Filed on Apr. 12, 2021, as Appl. No. 17/228,414.
Application 17/228,414 is a continuation of application No. PCT/US2019/055742, filed on Oct. 10, 2019.
Claims priority of provisional application 62/744,203, filed on Oct. 11, 2018.
Prior Publication US 2021/0369921 A1, Dec. 2, 2021
Int. Cl. A61L 29/08 (2006.01); A61M 25/00 (2006.01); C08L 27/18 (2006.01)
CPC A61L 29/085 (2013.01) [A61M 25/0009 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A medical device comprising:
one or more components comprised of one or more perfluorinated polymers and a liquid comprised of one or more perfluorinated liquids;
wherein at least a portion of a surface of the one or more components comprised of the one or more perfluorinated polymers comprises a surface layer of the one or more perfluorinated liquids;
wherein greater than 50% of a surface of the one or more components comprised of the one or more perfluorinated polymers that comprises a layer of the one or more perfluorinated liquids has a roughness as defined by a ratio of an actual surface area divided by a projected surface area that is greater than 1.00; wherein the roughness is determined in the absence of the one or more perfluorinated liquids;
wherein the one or more perfluorinated polymers comprises fluorinated ethylene propylene (FEP), polytetrafluoroethylene (PTFE), or a combination thereof; and
wherein the one or more perfluorinated liquids comprises perfluorodecalin, perfluorotributylamine or a combination thereof.