	US 12,233,160 B2
	Dried nanoparticle compositions
Steven Gregory Reed, Bellevue, WA (US); Amit Praful Khandhar, Issaquah, WA (US); and Darrick Albert Carter, Seattle, WA (US)
Assigned to HDT Bio Corp., Seattle, WA (US)
Filed by HDT Bio Corp., Seattle, WA (US)
Filed on Mar. 19, 2024, as Appl. No. 18/609,128.
Application 18/609,128 is a continuation of application No. PCT/US2022/013508, filed on Jan. 24, 2022.
Claims priority of provisional application 63/297,449, filed on Jan. 7, 2022.
Claims priority of provisional application 63/247,172, filed on Sep. 22, 2021.
Prior Publication US 2024/0216274 A1, Jul. 4, 2024
Int. Cl. A61K 9/107 (2006.01); A61K 9/19 (2006.01); A61K 9/51 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 47/06 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01); B82Y 5/00 (2011.01)

CPC A61K 9/1075 (2013.01) [A61K 9/19 (2013.01); A61K 9/5115 (2013.01); A61K 31/7105 (2013.01); A61K 31/711 (2013.01); A61K 47/06 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); B82Y 5/00 (2013.01)]

47 Claims

1. A dried composition of comprising:

a) a lipid carrier, wherein the lipid carrier is a nanoemulsion comprising a hydrophobic core, and one or more lipids, wherein the hydrophobic core comprises one or more inorganic nanoparticles, and wherein the one or more inorganic nanoparticles comprise magnetite (Fe₃O₄), maghemite (y-Fe₂O₃), wüstite (FeO), hematite (alpha (α)-Fe₂O₃), or combinations thereof;

b) optionally one or more nucleic acids; and

c) at least one sugar present in an amount of the composition by weight of 80% to 98%.