	US 12,233,144 B2
	Method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors
Anjing Lou, Seymour, CT (US); Teanoosh Moaddel, Watertown, CT (US); and Anil Babubhai Patel, Parsippany, NJ (US)
Assigned to Conopco, Inc., Englewood Cliffs, NJ (US)
Filed by Conopco, Inc., Englewood Cliffs, NJ (US)
Filed on Oct. 24, 2023, as Appl. No. 18/383,061.
Application 18/383,061 is a continuation of application No. 17/713,573, filed on Apr. 5, 2022, granted, now 11,826,449.
Application 17/713,573 is a continuation of application No. 16/099,450, granted, now 11,324,679, issued on Apr. 20, 2022, previously published as PCT/EP2017/060962, filed on May 8, 2017.
Claims priority of application No. 16169468 (EP), filed on May 12, 2016.
Prior Publication US 2024/0065953 A1, Feb. 29, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/34 (2006.01); A61G 19/00 (2006.01); A61K 8/06 (2006.01); A61K 8/35 (2006.01); A61K 8/36 (2006.01); A61K 8/67 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01)

CPC A61K 8/347 (2013.01) [A61G 19/00 (2013.01); A61K 8/062 (2013.01); A61K 8/361 (2013.01)]

12 Claims

1. A composition comprising:

(a) a retinoic acid precursor selected from retinyl propionate, hydroxyanasatil retinoate, and mixtures thereof; and

(b) a skin benefit agent selected from 4-ethyl resorcinol, 4-butyl resorcinol, 4-hexyl resorcinol, 4-isopropyl resorcinol and mixtures thereof; and

wherein the retinoic acid precursor and the skin benefit agent are present at a weight ratio of from about 1:2 to about 2:1; and

wherein the pH is from 4 to 8.

12. A method for impeding oxidation comprising a step of topically applying to skin the composition of claim 1.