US 12,233,120 B2
Proteins and immunizing compositions containing Pasteurella proteins and methods of use
Charles Nelson Carver, III, Willmar, MN (US); and Daryll Emery, Willmar, MN (US)
Assigned to Vaxxinova US, Inc., Willmar, MN (US)
Filed by VAXXINOVA US, INC., Willmar, MN (US)
Filed on May 31, 2023, as Appl. No. 18/203,917.
Application 18/203,917 is a continuation of application No. 17/191,913, filed on Mar. 4, 2021, granted, now 11,696,945.
Application 17/191,913 is a continuation of application No. 16/484,332, granted, now 10,967,056, issued on Apr. 6, 2021, previously published as PCT/US2018/017682, filed on Feb. 9, 2018.
Claims priority of provisional application 62/457,599, filed on Feb. 10, 2017.
Prior Publication US 2023/0414739 A1, Dec. 28, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 39/02 (2006.01); A61K 39/102 (2006.01); A61K 39/39 (2006.01); C07K 14/285 (2006.01); C07K 16/12 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01)
CPC A61K 39/102 (2013.01) [A61K 39/39 (2013.01); C07K 14/285 (2013.01); C07K 16/1242 (2013.01); G01N 33/56911 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55566 (2013.01); G01N 2333/285 (2013.01)] 15 Claims
 
1. A composition comprising a bacterium, the bacterium comprising:
(i) a protein having at least 90% similarity to amino acids 25-968 of SEQ ID NO: 2, a protein having at least 90% similarity to amino acids 27-780 of SEQ ID NO:4, and a protein having at least 90% similarity to amino acids 23-727 of SEQ ID NO:6; or
(ii) a protein having at least 90% similarity to amino acids 25-964 of SEQ ID NO: 8, a protein having at least 90% similarity to amino acids 26-848 of SEQ ID NO:10, a protein having at least 90% similarity to amino acids 27-784 of SEQ ID NO:12, and a protein having at least 90% similarity to amino acids 25-742 of SEQ ID NO:14; and
an adjuvant.