	US 12,233,097 B2
	Compositions and methods for promoting a healthy microbial flora in a mammal
Afif Ghannoum, Moreland Hills, OH (US)
Assigned to BIOHM Health Inc., Cleveland, OH (US)
Filed by BIOHM Health Inc., Cleveland, OH (US)
Filed on Mar. 9, 2022, as Appl. No. 17/690,879.
Application 17/690,879 is a division of application No. 16/468,053, granted, now 11,304,985, previously published as PCT/US2018/021794, filed on Mar. 9, 2018.
Claims priority of provisional application 62/556,016, filed on Sep. 8, 2017.
Claims priority of provisional application 62/470,060, filed on Mar. 10, 2017.
Prior Publication US 2022/0296662 A1, Sep. 22, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 36/064 (2006.01); A23L 31/00 (2016.01); A23L 33/135 (2016.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 9/48 (2006.01); A61K 9/50 (2006.01); A61K 35/00 (2006.01); A61K 35/745 (2015.01); A61K 35/747 (2015.01); A61K 38/47 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01)

CPC A61K 36/064 (2013.01) [A23L 31/00 (2016.08); A23L 33/135 (2016.08); A61K 9/0053 (2013.01); A61K 9/0056 (2013.01); A61K 9/19 (2013.01); A61K 9/4808 (2013.01); A61K 9/5047 (2013.01); A61K 35/745 (2013.01); A61K 35/747 (2013.01); A61K 38/47 (2013.01); A61P 31/04 (2018.01); A61P 31/10 (2018.01); C12Y 302/01001 (2013.01); A23V 2002/00 (2013.01); A23V 2400/113 (2023.08); A23V 2400/175 (2023.08); A23V 2400/519 (2023.08); A61K 2035/115 (2013.01)]

20 Claims

1. A method of improving nutrient absorption and inhibiting biofilm in a subject, the method comprising consumption by, or administration to, the subject of a probiotic composition comprising (i) an isolated non-pathogenic fungal strain Saccharomyces boulardii; (ii) isolated non-pathogenic bacterial strains comprising Lactobacillus rhamnosus, Bifidobacterium breve, and Lactobacillus acidophilus; and (iii) an enzyme, thereby improving nutrient absorption and inhibiting biofilm in the subject.