US 12,233,076 B2
Stable liquid formulations of cyclophosphamide and processes to prepare the same
Riyaz Ahmed Shaik, Hyderabad (IN); Ananya Saha, Asansol (IN); Svb Janardhan Garikipati, Visakhapatnam (IN); Akash Chaurasiya, Agra (IN); Bhavesh Vallabhbhai Patel, Hyderabad (IN); Harshal Bhagwatwar, Hyderabad (IN); and Sumitra Ashok Pillai, Ahmedabad (IN)
Assigned to Avyxa Holdings, LLC, San Juan, PR (US)
Filed by DR. REDDY'S LABORATORIES LIMITED, Hyderabad (IN)
Filed on Jun. 3, 2022, as Appl. No. 17/831,926.
Application 17/831,926 is a division of application No. 15/402,712, filed on Jan. 10, 2017, granted, now 11,382,923.
Application 15/402,712 is a continuation in part of application No. PCT/IB2015/055285, filed on Jul. 13, 2015.
Claims priority of application No. 3454/CHE/2014 (IN), filed on Jul. 11, 2014; and application No. 5215/CHE/2014 (IN), filed on Oct. 17, 2014.
Prior Publication US 2022/0296617 A1, Sep. 22, 2022
Int. Cl. A61K 31/664 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/19 (2006.01); A61K 31/675 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61K 47/44 (2017.01); B01D 15/08 (2006.01)
CPC A61K 31/664 (2013.01) [A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 9/19 (2013.01); A61K 31/675 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61K 47/44 (2013.01); B01D 15/08 (2013.01)] 36 Claims
 
1. A process for preparing a stable liquid formulation of cyclophosphamide, wherein the process comprises reducing the moisture content from cyclophosphamide or liquid compositions of cyclophosphamide or both by a drying process or by means of adsorbents.