	US 12,232,951 B2
	Optical material and method for modifying the refractive index
Wayne H. Knox, Rochester, NY (US); Li Ding, San Jose, CA (US); Jay F. Kunzler, Canandaigua, NY (US); and Dharmendra Jani, Keller, TX (US)
Assigned to University of Rochester, Rochester, NY (US)
Filed by University of Rochester, Rochester, NY (US)
Filed on Jan. 15, 2021, as Appl. No. 17/150,546.
Application 16/388,992 is a division of application No. 15/455,870, filed on Mar. 10, 2017, granted, now 10,299,909, issued on May 28, 2019.
Application 14/564,207 is a division of application No. 13/686,952, filed on Nov. 28, 2012, granted, now 8,932,352, issued on Jan. 13, 2015.
Application 12/846,950 is a division of application No. 11/948,298, filed on Nov. 30, 2007, granted, now 7,789,910, issued on Sep. 7, 2010.
Application 17/150,546 is a continuation of application No. 16/388,992, filed on Apr. 19, 2019, granted, now 10,893,936.
Application 15/455,870 is a continuation of application No. 14/564,207, filed on Dec. 9, 2014, granted, now 9,622,912, issued on Apr. 18, 2017.
Application 13/686,952 is a continuation of application No. 12/846,950, filed on Jul. 30, 2010, granted, now 8,337,553, issued on Dec. 25, 2012.
Application 11/948,298 is a continuation in part of application No. 11/745,746, filed on May 8, 2007, abandoned.
Claims priority of provisional application 60/817,027, filed on Jun. 28, 2006.
Prior Publication US 2021/0128294 A1, May 6, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/14 (2006.01); A61B 18/20 (2006.01); A61F 2/16 (2006.01); A61F 9/008 (2006.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); A61L 27/52 (2006.01); B29D 11/00 (2006.01); B29D 11/02 (2006.01); B29K 83/00 (2006.01); B29K 105/00 (2006.01); C08J 7/12 (2006.01); G02B 1/04 (2006.01); G02C 7/02 (2006.01)

CPC A61F 2/14 (2013.01) [A61B 18/20 (2013.01); A61F 2/142 (2013.01); A61F 2/1451 (2015.04); A61F 2/147 (2013.01); A61F 2/16 (2013.01); A61F 2/1627 (2013.01); A61F 9/008 (2013.01); A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/52 (2013.01); B29D 11/00355 (2013.01); B29D 11/00461 (2013.01); B29D 11/00769 (2013.01); B29D 11/023 (2013.01); C08J 7/12 (2013.01); C08J 7/123 (2013.01); G02B 1/041 (2013.01); G02C 7/022 (2013.01); B29K 2083/00 (2013.01); B29K 2105/0061 (2013.01); C08J 2333/14 (2013.01); C08J 2339/06 (2013.01); C08J 2383/04 (2013.01); G02C 2202/12 (2013.01); G02C 2202/14 (2013.01)]

12 Claims

1. An optical device in the form of a contact lens, an intraocular lens, a corneal inlay, a corneal ring, or a keratoprothesis, comprising a completely polymerized optical hydrogel polymeric material with select regions within the completely polymerized optical hydrogel material that have been irradiated with laser light from a focused, visible or near-IR laser having a pulse energy from 0.01 nJ to 1000 nJ and a wavelength from 400 nm to 1500 nm while the optical hydrogel material is in an already completely polymerized condition, and non-irradiated regions within the completely polymerized optical hydrogel material that have not been irradiated with the laser light, wherein the irradiated regions are in the form of at least one area or volume filled structure formed by scanning the laser light over the select regions of the already completely polymerized optical hydrogel material and which are characterized by a change in refractive index in the irradiated regions relative to the refractive index of the completely polymerized optical hydrogel material in the non-irradiated regions.