US 12,232,944 B2
Chitosan tubular member and method of producing
Rachel Dekeyser, Cleveland, OH (US); Lisa Heller, Cleveland, OH (US); Ben Cottrill, Cleveland, OH (US); Derek Lewis, Cleveland, OH (US); and Rachel Smith, Cleveland, OH (US)
Assigned to CHECKPOINT SURGICAL, INC., Independence, OH (US)
Appl. No. 18/684,712
Filed by CHECKPOINT SURGICAL, INC., Cleveland, OH (US)
PCT Filed Aug. 3, 2023, PCT No. PCT/US2023/029360
§ 371(c)(1), (2) Date Feb. 19, 2024,
PCT Pub. No. WO2024/044026, PCT Pub. Date Feb. 29, 2024.
Claims priority of provisional application 63/401,204, filed on Aug. 26, 2022.
Prior Publication US 2024/0325135 A1, Oct. 3, 2024
Int. Cl. A61F 2/00 (2006.01)
CPC A61F 2/0063 (2013.01) [A61F 2002/0068 (2013.01); A61F 2002/0072 (2013.01); A61F 2210/0004 (2013.01); A61F 2210/0014 (2013.01); A61F 2210/0057 (2013.01); A61F 2210/0061 (2013.01); A61F 2210/0076 (2013.01); A61F 2220/005 (2013.01); A61F 2220/0075 (2013.01); A61F 2230/0019 (2013.01); A61F 2230/0026 (2013.01); A61F 2230/0069 (2013.01); A61F 2240/001 (2013.01); A61F 2250/0036 (2013.01); A61F 2250/0037 (2013.01); A61F 2250/0039 (2013.01); A61F 2250/0059 (2013.01)] 54 Claims
OG exemplary drawing
 
1. A method of repairing a nerve or tendon comprising:
forming a biodegradable sheet from a composition comprising chitosan, the composition configured to dissolve within 1 to 21 months after the biodegradable sheet is formed;
wrapping the biodegradable sheet around a mandrel having a preselected size and shape to form a synthetic guide;
disposing the synthetic guide around an injured nerve or tendon; and
placing the mandrel wrapped with the biodegradable sheet in a forming shell, wherein the forming shell has a textured finish along interfaces where the forming shell comes into physical contact with the mandrel wrapped with the biodegradable sheet.