US 12,232,902 B1
Targeting coronary revascularization based on myocardial viability
Travis Pollema, Oakland, CA (US); Gordon Ho, Oakland, CA (US); Robert Joseph Krummen, Bellevue, WA (US); Christopher J. T. Villongco, Oakland, CA (US); and Christian David Marton, Jersey City, NJ (US)
Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; and THE VEKTOR GROUP, INC.
Filed by The Vektor Group Inc., San Diego, CA (US); and The Regents of the University of California, Oakland, CA (US)
Filed on Jun. 10, 2024, as Appl. No. 18/739,199.
Claims priority of provisional application 63/516,862, filed on Aug. 1, 2023.
Int. Cl. A61B 6/50 (2024.01); A61B 6/00 (2024.01); A61B 6/03 (2006.01); A61B 6/46 (2024.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06T 7/62 (2017.01); G06T 17/20 (2006.01)
CPC A61B 6/503 (2013.01) [A61B 6/032 (2013.01); A61B 6/466 (2013.01); A61B 6/504 (2013.01); A61B 6/507 (2013.01); A61B 6/5217 (2013.01); G06T 7/0012 (2013.01); G06T 7/11 (2017.01); G06T 7/62 (2017.01); G06T 17/20 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/20072 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30048 (2013.01); G06T 2207/30104 (2013.01)] 30 Claims
OG exemplary drawing
 
1. A method performed by one or more computing systems for generating a revascularization score for a blockage of a coronary artery of the heart of a patient, the method comprising:
accessing myocardial tissue state of the myocardium of the heart, the myocardial tissue state indicating viability of the myocardial tissue;
accessing an indication of a blockage state of a blockage of a coronary artery of the patient, the blockage state indicating a blockage location and a blockage amount of the blockage;
accessing an indication of a perfusion territory of the blockage, the perfusion territory being the myocardial tissue that is perfused by normal blood flow with no blockage through the blockage location;
generating a three-dimensional (3D) mesh based on imaging of the heart, the 3D mesh representing voxels within the myocardium of the heart;
for each of a plurality of voxels within the perfusion territory, associating that voxel with a myocardial tissue state;
generating a revascularization score for the blockage based on myocardial tissue state associated with the voxels within the perfusion territory and-the blockage state, the revascularization score providing an assessment of benefit to myocardial tissue resulting from the revascularization of the blockage;
generating a graphic of the heart based on the 3D mesh that indicates one or more of the coronary arteries, the myocardial tissue state within the perfusion territory, the blockage state, and the revascularization score; and displaying the graphic.