US 12,232,522 B2
Method of generating an aerosol having protonated nicotine
Connor Bruton, London (GB); Anna Azzopardi, London (GB); and Peter Clayton, London (GB)
Assigned to NICOVENTURES TRADING LIMITED, London (GB)
Appl. No. 17/293,934
Filed by NICOVENTURES TRADING LIMITED, London (GB)
PCT Filed Nov. 15, 2019, PCT No. PCT/GB2019/053233
§ 371(c)(1), (2) Date May 14, 2021,
PCT Pub. No. WO2020/099880, PCT Pub. Date May 22, 2020.
Claims priority of application No. 1818711 (GB), filed on Nov. 16, 2018.
Prior Publication US 2022/0007715 A1, Jan. 13, 2022
Int. Cl. A24F 40/10 (2020.01); A24B 15/167 (2020.01); A24F 40/30 (2020.01); A24F 40/42 (2020.01)
CPC A24F 40/10 (2020.01) [A24B 15/167 (2016.11); A24F 40/30 (2020.01); A24F 40/42 (2020.01)] 12 Claims
OG exemplary drawing
 
1. A method of generating an aerosol comprising protonated nicotine, the method comprising the steps of:
(i) providing a nicotine formulation comprising nicotine as a free base form;
(ii) providing a carbon dioxide source capable of providing carbon dioxide in situ;
(iii) vaporizing or aerosolizing the nicotine formulation;
(iv) providing carbon dioxide from the carbon dioxide source; and
(v) contacting the carbon dioxide with the vaporized or aerosolized nicotine formulation to thereby protonate nicotine free base and generate an aerosol comprising protonated nicotine;
wherein the nicotine formulation contains the carbon dioxide source.