US 11,908,551 B2
System and method for identifying potential targets for pharmaceutical compound
Gaurav Tripathi, Pune (IN); Om Sharma, Dhanbad (IN); Vatsal Agarwal, Rampur (IN); and Anurag Chandrekar, Raipur (IN)
Assigned to INNOPLEXUS AG, Eschborn (DE)
Filed by Innoplexus AG, Eschborn (DE)
Filed on Mar. 27, 2019, as Appl. No. 16/366,142.
Claims priority of application No. 1804870 (GB), filed on Mar. 27, 2018.
Prior Publication US 2020/0090789 A1, Mar. 19, 2020
Int. Cl. G16C 20/50 (2019.01); G16B 15/30 (2019.01); G16C 20/60 (2019.01); G16B 5/00 (2019.01); G16B 50/30 (2019.01); G16C 20/30 (2019.01); G16C 20/90 (2019.01); G16C 20/70 (2019.01)
CPC G16C 20/50 (2019.02) [G16B 5/00 (2019.02); G16B 50/30 (2019.02); G16C 20/30 (2019.02); G16C 20/60 (2019.02); G16C 20/70 (2019.02); G16C 20/90 (2019.02)] 11 Claims
OG exemplary drawing
 
1. A system that identifies potential targets for a pharmaceutical compound, wherein the system includes a computer system, wherein the system comprises:
a database arrangement operable to store existing data sources and information related to the pharmaceutical compound; and
a processing module communicably coupled to the database arrangement, the processing module operable to:
receive information related to the pharmaceutical compound, wherein the information comprises at least one known target associated with the pharmaceutical compound;
extract plurality of targets from existing data sources, wherein the existing data sources comprises plurality of data records and wherein each of the plurality of targets is associated with the same pharmaceutical compound in each of the plurality of data records;
analyse druggability of each of the plurality of targets to determine a preliminary set of targets;
determine a net score for each of the targets in the preliminary set of targets; and
identify targets with the net score above a predefined threshold, as the potential targets, wherein the potential targets correspond to unidentified sites of action for the pharmaceutical compound.