CPC C12N 9/90 (2013.01) [A61K 31/167 (2013.01); A61K 31/436 (2013.01); A61K 38/15 (2013.01); A61K 47/55 (2017.08); C07K 14/4702 (2013.01); C12N 9/22 (2013.01); C12N 15/111 (2013.01); C12N 2310/20 (2017.05)] | 8 Claims |
1. A bifunctional chemical epigenetic modifier (CEM) comprising a molecule of FK506 or derivative thereof, a linker and a histone deacetylase inhibitor, wherein the histone deacetylase inhibitor is suberanilohydroxamic acid, depsipeptide or a derivative thereof.
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