CPC A61K 31/4439 (2013.01) [A61K 31/122 (2013.01); A61K 31/137 (2013.01); A61K 31/155 (2013.01); A61K 31/366 (2013.01); A61K 31/4196 (2013.01); A61K 31/473 (2013.01); A61K 31/4706 (2013.01); A61K 31/4709 (2013.01); A61K 31/4745 (2013.01); A61K 31/65 (2013.01); A61P 33/06 (2018.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01)] | 24 Claims |
1. A compound according to Formula (I):
![]() wherein R1 is an optionally substituted 5-membered heterocycle; R2 is H or both R2 are joined to form an optionally substituted cyclopropyl; R3 is selected from an optionally substituted monocyclic aryl and an optionally substituted heteroaryl; pharmaceutically acceptable salts, hydrates, tautomers, racemic mixtures, or optically active forms thereof, wherein the term substituted refers to a group substituted with from 1 to 5 substituents selected from the group consisting of C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8-cycloalkyl, heterocycloalkyl, C1-C6 alkyl aryl, C1-C6 alkyl heteroaryl, C1-C6 alkyl C3-C8-cycloalkyl, C1-C6 alkyl heterocycloalkyl, acyl, amino, amide, aminosulfonyl, ammonium, acyl amino, aminocarbonyl, aryl, heteroaryl, sulfinyl, sulfonyl, sulphonamide, alkoxy, alkoxy carbonyl, carbamate, sulfanyl, halogen, trihalomethyl, cyano, hydroxy, mercapto, and nitro.
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