US 11,903,721 B1
Digital apparatus and application for treating mild cognitive impairment and dementia
Seung Eun Choi, Seoul (KR)
Filed by S-Alpha Therapeutics, Inc., Seoul (KR)
Filed on Dec. 16, 2022, as Appl. No. 18/082,722.
Application 18/082,722 is a continuation of application No. 16/860,641, filed on Apr. 28, 2020, abandoned.
Int. Cl. A61B 5/00 (2006.01)
CPC A61B 5/4088 (2013.01) [A61B 5/7465 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A method of treating a patient with mild cognitive impairment (MCI) or dementia by one or more digital therapeutics, the method comprising:
providing one or more first digital instructions to the patient to improve one or more neurohumoral factors that cause the MCI or the dementia of the patient,
detecting at least one neurohumoral change among the one or more neurohumoral factors occurring because of the patient's performance of the one or more first digital instructions,
detecting the patient's adherence to the one or more first digital instructions using a sensor, and
generating one or more second digital instructions to treat at least one imbalance of the one or more neurohumoral factors based on the at least one neurohumoral change and the adherence,
wherein the one or more neurohumoral factors comprises at least one of sex steroid hormone, insulin-like growth factor-2 (IGF-2), β-catenin in Wnt signaling, Bcl-2—associated athanogene 1 (BAG1), cAMP response element-binding protein (CREB), inflammation factors, corticosteroids, or neurohormones.