| CPC H04N 25/134 (2023.01) [A61B 1/00006 (2013.01); A61B 1/00009 (2013.01); A61B 1/0005 (2013.01); A61B 1/00193 (2013.01); A61B 1/043 (2013.01); A61B 1/05 (2013.01); A61B 1/06 (2013.01); A61B 1/0638 (2013.01); A61B 1/0646 (2013.01); G06T 3/4015 (2013.01); H04N 5/265 (2013.01); H04N 13/257 (2018.05); H04N 23/10 (2023.01); H04N 23/45 (2023.01); H04N 23/56 (2023.01); H04N 23/57 (2023.01); H04N 23/555 (2023.01)] | 20 Claims |

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1. A method comprising:
causing an illuminator to simultaneously illuminate tissue with a first visible color illumination component, a second visible color illumination component, and a fluorescence excitation illumination component;
causing a display unit to display, based on the illumination, a display scene that includes:
a reduced color scene component corresponding to the first and second visible color illumination components, and
a highlighted scene component corresponding to the fluorescence excitation illumination component; and
receiving a single frame, the single frame comprising:
a first set of pixel data that includes a fluorescence scene component associated with the fluorescence excitation illumination component,
a second set of pixel data that includes a combination of a first visible color component scene and the fluorescence scene component, the first visible color component scene associated with the first visible color illumination component, and
a third set of pixel data that includes a combination of a second visible color component scene and the fluorescence scene component, the second visible color component scene associated with the second visible color illumination component;
wherein the causing the display unit to display the display scene is based on the first, second, and third sets of pixel data.
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