US 12,230,400 B2
Determining a cardiovascular ischemic event and decision support tool
Douglas S. McNair, Leawood, KS (US)
Assigned to Cerner Innovation, Inc., Kansas City, MO (US)
Filed by Cerner Innovation, Inc., Kansas City, MO (US)
Filed on Jan. 31, 2024, as Appl. No. 18/429,058.
Application 18/429,058 is a continuation of application No. 16/141,682, filed on Sep. 25, 2018, granted, now 11,942,219.
Claims priority of provisional application 62/562,761, filed on Sep. 25, 2017.
Prior Publication US 2024/0170148 A1, May 23, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. G16H 50/20 (2018.01); G01N 33/68 (2006.01); G16H 10/60 (2018.01); G16H 40/63 (2018.01)
CPC G16H 50/20 (2018.01) [G01N 33/6893 (2013.01); G16H 40/63 (2018.01); G01N 2333/4737 (2013.01); G01N 2800/32 (2013.01); G01N 2800/52 (2013.01); G16H 10/60 (2018.01)] 20 Claims
OG exemplary drawing
 
1. An electronic medical record (EMR) system for determining a cardiovascular ischemic event, the EMR system associated with a patient and comprising one or more processors configured to cause a plurality of operations, the operations comprising:
collecting via a measurement device and recording, in a digital memory, measurement data comprising values for one or both of select blood variables associated with the patient and select serum variables associated with the patient, the values comprising a series of C-reactive protein (CRP) measurements and a series of uric acid measurements;
in response to detecting a set of constant values in the measurement data, abstaining from processing the measurement data for an interval of time;
initiating, after passage of the interval of time, by the EMR system:
identifying CRP and uric acid log-return time series from the series of CRP measurements and uric acid measurements, respectively;
utilizing the CRP log-return time series and the uric acid log-return time series to determine a transfer energy and a spectral coherence;
generating a composite index for an ischemic event based on the transfer energy and based further on the spectral coherence;
evaluating the composite index against a threshold associated with CRP and uric acid physiological parameters;
based on evaluating the composite index against the threshold, automatically diagnosing cardiovascular ischemia, by an EMR, without arterial anatomy being measured by invasive or imaging modalities; and
determining a particular treatment, for the patient based on the automatic diagnosing of cardiovascular ischemia to administer to the patient to treat the cardiovascular ischemia of the patient.