| CPC G06T 5/70 (2024.01) [A61B 6/481 (2013.01); A61B 6/504 (2013.01); A61B 6/5264 (2013.01); G06T 5/50 (2013.01); G06T 7/0016 (2013.01); G06T 2207/20182 (2013.01); G06T 2207/20224 (2013.01); G06T 2207/30104 (2013.01)] | 20 Claims |

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1. A method for generating a subtraction image for digital subtraction angiography, the method comprising:
obtaining a plurality of mask images of an object before administering a contrast agent into the object;
obtaining a map of the object after administering a contrast agent into the object;
forming a first sum image from the plurality of mask images, wherein the plurality of mask images is summed in each case multiplied by an individual weighting, wherein the individual weightings for each of the plurality of mask images are automatically determined by an optimization method; and
ascertaining the subtraction image by subtraction of the sum image from the map.
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