US 12,228,565 B2
Blood cell lysis compositions and uses thereof
Miklos Erdosy, Groton, MA (US); Hyoungsik Yim, Melrose, MA (US); Emily McDowell, Indianapolis, IN (US); and Prasad V. A. Pamidi, Burlington, MA (US)
Assigned to Instrumentation Laboratory Company, Bedford, MA (US)
Filed by Instrumentation Laboratory Company, Bedford, MA (US)
Filed on Jun. 16, 2021, as Appl. No. 17/348,934.
Prior Publication US 2022/0412951 A1, Dec. 29, 2022
Int. Cl. G01N 33/49 (2006.01); G01N 1/40 (2006.01); G01N 33/72 (2006.01)
CPC G01N 33/491 (2013.01) [G01N 1/4044 (2013.01); G01N 33/721 (2013.01); G01N 33/728 (2013.01)] 17 Claims
 
1. A blood cell lysis composition comprising:
a buffer; and
a secondary alcohol ethoxylate at a concentration between 9% weight per volume (w/v) and 20% w/V;
wherein the secondary alcohol ethoxylate comprises one or more of:
a first secondary alcohol ethoxylate having the following structural formula where x is 5, 7, 9, 11, 12, 13, 14, or 15,

OG Complex Work Unit Chemistry
a second secondary alcohol ethoxylate having the following structural formula where n is 6, 10, 11, 12, 13, 14, or 15,

OG Complex Work Unit Chemistry