US 12,228,514 B1
Systems, devices, and methods for virus detection via fluorescence emission
Carlos Roberto Resquin, Buenos Aires (AR)
Assigned to A9.com, Inc., Palo Alto, CA (US)
Filed by A9.com, Inc., Palo Alto, CA (US)
Filed on Apr. 7, 2021, as Appl. No. 17/224,774.
Claims priority of provisional application 63/135,139, filed on Jan. 8, 2021.
Int. Cl. G01N 21/64 (2006.01); C12Q 1/70 (2006.01)
CPC G01N 21/6428 (2013.01) [C12Q 1/70 (2013.01); G01N 21/6456 (2013.01); G01N 2021/6471 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A system for detecting one or more viruses, the system comprising:
a fluorescence detection device comprising one or more excitation light emitters, an image capture device, and a sample tube rack configured to receive sample tubes and to support the sample tubes; wherein the fluorescence detection device is configured to receive the sample tubes and to support the sample tubes in controlled positions relative to the image capture device; and
a computing device comprising a display, wherein the computing device is configured to execute an analysis and control application which, when executed, causes the computing device to: display guidance instructions on the display indicative of a correct prescribed positioning of the sample tubes in the sample tube rack; to control an operation of the one or more excitation light emitters to emit an excitation light onto samples disposed in sample tubes; to control an operation of the image capture device to capture an image of a fluorescence emitted by each sample in the sample tubes in response to the excitation light emitted onto the samples in the sample tubes; and to receive and to process the image to quantify the fluorescence emitted by each sample in the sample tubes to determine one or more detection results indicative of one or more positive detections of the one or more viruses in the samples in the sample tubes, one or more negative detections of the one or more viruses in the samples in the sample tube, or one or more invalid detections of the one or more viruses in the samples in the sample tubes.