US 12,228,512 B2
Multipurpose microfluidics devices for rapid on-site optical chemical analysis
Hooisweng Ow, Woburn, MA (US); Sehoon Chang, Brighton, MA (US); Jason R. Cox, Ashland, MA (US); Bora Yoon, Houston, TX (US); and Wei Wang, Quincy, MA (US)
Assigned to Saudi Arabian Oil Company, Dhahran (SA)
Filed by Saudi Arabian Oil Company, Dhahran (SA)
Filed on Jul. 16, 2020, as Appl. No. 16/931,143.
Claims priority of provisional application 62/874,652, filed on Jul. 16, 2019.
Prior Publication US 2021/0018436 A1, Jan. 21, 2021
Int. Cl. G01N 21/64 (2006.01); B01L 3/00 (2006.01); G01N 1/40 (2006.01); G01N 33/28 (2006.01)
CPC G01N 21/6408 (2013.01) [B01L 3/502715 (2013.01); G01N 1/405 (2013.01); G01N 33/2823 (2013.01); B01L 2300/126 (2013.01); B01L 2300/161 (2013.01)] 24 Claims
OG exemplary drawing
 
1. A device for chemical analysis of a fluid sample, the device comprising:
a first separation element formed on a substrate for receiving the fluid sample, the first separation element comprising a hydrophilic channel with a hydrophobic border that separates water from hydrocarbons in the fluid sample, the hydrophobic border at least partially surrounding the first separation element;
a plurality of second separation elements fluidically connected to the first separation element and formed on the substrate, each second separation element comprising a wicking channel with a different functionalized surface configured to react with and separate a different component from the fluid sample such that each second separation element reacts with and separates different components from the fluid sample; and
a different detection element fluidically connected to each second separation element and formed on the substrate, each detection element having a surface comprising one or more lanthanide ions that emit a fluorescence signal upon binding with one or more analytes present in the fluid sample, each emitted fluorescence signal indicative of a different analyte and capable of being optically detected by a detector.