US 12,228,488 B2
Device and method for measuring micro/nano-sized particles
Ke Liu, Shenzhen (CN); Gui Xiong, Shenzhen (CN); and Zhe Wang, Shenzhen (CN)
Assigned to Resun (Shenzhen) Tech Co., Ltd., Shenzhen (CN)
Appl. No. 17/757,888
Filed by RESUN (SHENZHEN) TECH CO., LTD., Shenzhen (CN)
PCT Filed Nov. 12, 2020, PCT No. PCT/CN2020/128400
§ 371(c)(1), (2) Date Jun. 23, 2022,
PCT Pub. No. WO2021/098583, PCT Pub. Date May 27, 2021.
Claims priority of application No. 201911158297.3 (CN), filed on Nov. 22, 2019.
Prior Publication US 2023/0236104 A1, Jul. 27, 2023
Int. Cl. G01N 15/02 (2024.01); G01N 15/00 (2024.01)
CPC G01N 15/0266 (2013.01) [G01N 2015/0038 (2013.01); G01N 2015/0294 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A method for measuring micro/nano-sized particles, the method is applied to a device for measuring micro/nano-sized particles, wherein the device comprises a cavity and at least two microporous membranes, wherein the microporous membranes are arranged in series in the cavity and divide the cavity into a plurality of chambers, wherein each of the microporous membranes is provided with micropores, and two adjacent chambers are in communication via the micropores, and wherein each of the chambers is provided with an electrode, and the method allows the micro/nano-sized particles to be measured to continuously pass through micropores of the device with an electrolyte solution, the method comprising:
acquiring electrical signal data between two electrodes adjacent to each of the micropores in the process of the micro/nano-sized particles passing through each of the micropores;
determining attribute data of the micro/nano-sized particles according to the electrical signal data;
wherein determining attributes data of the micro/nano-sized particles according to the electrical signal data comprising:
dividing the electrical signal data into a plurality of signal units;
comparing each the signal unit with the corresponding signal unit of a standard signal respectively, to obtain a contrast coefficient between the electrical signal data and the standard signal;
acquiring the sphericity value corresponding to the standard signal with the highest contrast coefficient as the sphericity value of the micro/nano-sized particles.