US 12,227,897 B2
Silk performance apparel and products and methods of preparing the same
Gregory H. Altman, Providence, RI (US); and Enrico Mortarino, Hickory, NC (US)
Assigned to EVOLVED BY NATURE, INC., Needham, MA (US)
Filed by Evolved by Nature, Inc., Medford, MA (US)
Filed on Mar. 7, 2023, as Appl. No. 18/179,869.
Application 18/179,869 is a continuation of application No. 16/356,550, filed on Mar. 18, 2019, granted, now 11,649,585.
Application 16/356,550 is a continuation of application No. 15/179,846, filed on Jun. 10, 2016, granted, now 10,287,728, issued on May 14, 2019.
Application 15/179,846 is a continuation of application No. 14/958,565, filed on Dec. 3, 2015, granted, now 10,301,768, issued on May 28, 2019.
Application 14/958,565 is a continuation of application No. PCT/US2015/063545, filed on Dec. 2, 2015.
Claims priority of provisional application 62/245,221, filed on Oct. 22, 2015.
Claims priority of provisional application 62/192,477, filed on Jul. 14, 2015.
Prior Publication US 2023/0220614 A1, Jul. 13, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. D06M 15/15 (2006.01); A41D 13/00 (2006.01); A41D 31/00 (2019.01); A41D 31/18 (2019.01); A61K 8/64 (2006.01); A61Q 19/00 (2006.01); D06N 7/00 (2006.01)
CPC D06M 15/15 (2013.01) [A41D 13/0015 (2013.01); A41D 31/00 (2013.01); A41D 31/185 (2019.02); A61K 8/64 (2013.01); A61Q 19/00 (2013.01); D06N 7/00 (2013.01); D06M 2200/50 (2013.01); D06N 2203/02 (2013.01); D10B 2401/02 (2013.01)] 28 Claims
OG exemplary drawing
 
1. An article comprising a fabric having a coating, the coating comprising silk fibroin protein fragments having a weight average molecular weight selected from about 140 kDa to about 145 kDa, from about 145 kDa to about 150 kDa, from about 150 kDa to about 155 kDa, from about 155 kDa to about 160 kDa, from about 160 kDa to about 165 kDa, from about 165 kDa to about 170 kDa, from about 170 kDa to about 175 kDa, from about 175 kDa to about 180 kDa, from about 180 kDa to about 185 kDa, from about 185 kDa to about 190 kDa, from about 190 kDa to about 195 kDa, or from about 195 kDa to about 200 kDa, and a polydispersity between 1 and about 5,
wherein the silk fibroin protein fragments, prior to coating the fabric, do not spontaneously or gradually gelate and do not visibly change in color or turbidity when in a solution for at least 10 days.