	US 12,227,546 B2
	Plasmid encoding a c-terminal fragment of paraspeckle component 1 for treating tumors
Yuh-Shan Jou, Taipei (TW); Yaw-Dong Lang, Taipei (TW); and Hsi-Wen Yeh, Tainan (TW)
Assigned to ACADEMIA SINICA, Taipei (TW)
Appl. No. 16/970,350
Filed by Academia Sinica, Taipei (TW)
PCT Filed Feb. 12, 2019, PCT No. PCT/US2019/017591 § 371(c)(1), (2) Date Aug. 15, 2020, PCT Pub. No. WO2019/160840, PCT Pub. Date Aug. 22, 2019.
Claims priority of provisional application 62/631,503, filed on Feb. 16, 2018.
Prior Publication US 2021/0087239 A1, Mar. 25, 2021
Int. Cl. C12N 15/00 (2006.01); A61K 48/00 (2006.01); C07K 14/47 (2006.01); C12N 15/63 (2006.01); A61K 38/00 (2006.01)

CPC C07K 14/4702 (2013.01) [A61K 48/0041 (2013.01); A61K 48/005 (2013.01); C12N 15/63 (2013.01); A61K 38/00 (2013.01)]

7 Claims

1. An isolated plasmid comprising a nucleic acid sequence encoding a C-terminal fragment of paraspeckle component 1 (PSPC1) consisting of the amino acid sequence of SEQ ID NO: 3 that has antitumor activity against tumor cells.