US 12,227,480 B1
1-(2-(substituted phenyl)-2-oxoethyl)-4-methylpyridin-1-ium bromide as anti-tubercular agents
Katharigatta N. Venugopala, Al-Ahsa (SA); Melendran Pillay, Durban (ZA); Pran Kishore Deb, Ranchi (IN); Mohamed A. Morsy, Al-Ahsa (SA); Sandeep Chandrashekarappa, Uttar Pradesh (IN); and Bandar Aldhubiab, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Oct. 6, 2023, as Appl. No. 18/377,407.
Int. Cl. C07D 213/20 (2006.01); A61K 31/06 (2006.01); A61K 31/4425 (2006.01); A61P 31/06 (2006.01)
CPC C07D 213/20 (2013.01) [A61K 31/4425 (2013.01); A61P 31/06 (2018.01)] 5 Claims
 
1. A method of treating tuberculosis in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a compound having the formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
R1 is selected from the group consisting of Br and F.