a nucleic acid extraction cartridge (100) configured to extract a nucleic acid of a biological sample via a nucleic acid extraction reagent stored therein;

a PCR plate (200) having a channel coupled to the nucleic acid extraction cartridge and at least one reaction well (W) which accommodates a PCR dried mixture containing a primer, a primer/probe, or a primer probe and receives a nucleic acid solution extracted from the nucleic acid extraction cartridge (100); and

a temperature control module (300) disposed above the PCR plate (200), adjacent to the reaction well (W) to apply different temperatures, and having a pair of heating blocks (310, 320) that are movable horizontally and vertically,

wherein the temperature control module (300) includes:

a first heat block including a first pressing surface (G1) corresponding to a surface of the reaction well and maintained at a temperature (hereinafter, referred to as a “first temperature” required for denaturation;

a second heating block (320) disposed at a position corresponding to the first heating block (310) and spaced apart from the first heating block (310), including a second pressing surface (G2) corresponding to the surface of the reaction well, and maintained at a temperature (hereinafter, referred to as a “second temperature”) required for annealing; and

a drive module (330) configured to perform horizontal movements and vertical movements of the first heating block (310) and the second heating block (320).