	US 12,226,746 B2
	Reversing bias in polymer synthesis electrode array
Bichlien Nguyen, Seattle, WA (US); Karin Strauss, Seattle, WA (US); Gagan Gupta, Bellevue, WA (US); and Richard Rouse, Redmond, WA (US)
Assigned to MICROSOFT TECHNOLOGY LICENSING, LLC, Redmond, WA (US)
Filed by MICROSOFT TECHNOLOGY LICENSING, LLC, Redmond, WA (US)
Filed on Jun. 7, 2019, as Appl. No. 16/435,363.
Prior Publication US 2020/0384434 A1, Dec. 10, 2020
Int. Cl. B01J 19/00 (2006.01)

CPC B01J 19/0046 (2013.01) [B01J 19/0006 (2013.01); B01J 2219/0018 (2013.01); B01J 2219/00454 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00612 (2013.01); B01J 2219/00626 (2013.01); B01J 2219/00637 (2013.01); B01J 2219/00653 (2013.01); B01J 2219/00713 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00725 (2013.01)]

19 Claims

1. A method for selectively releasing polymers from a solid support comprising an array of spatially addressable electrodes, the method comprising:

synthesizing the polymers directly on the solid support or directly on linkers attached to the solid support;

reversing voltage and current on part of the array of spatially addressable electrodes, wherein the polymers separate from the solid support only at locations on the solid support corresponding to spatially addressable electrodes where voltage and current are reversed;

returning the voltage and current of the part of the array of spatially addressable electrodes to an original voltage and current; and

initiating synthesis of additional polymers on the locations on the solid support corresponding to the spatially addressable electrodes where the voltage and current were previously reversed.