US 12,226,631 B2
Non invasive neuromodulation device for enabling recovery of motor, sensory, autonomic, sexual, vasomotor and cognitive function
Victor Reggie Edgerton, Los Angeles, CA (US); Yuri P. Gerasimenko, Los Angeles, CA (US); Nicholas A. Terrafranca, Laguna Nigel, CA (US); and Daniel C. Lu, Rancho Palos Verdes, CA (US)
Assigned to The Regents of The University of California, Oakland, CA (US)
Filed by The Regents of The University of California, Oakland, CA (US)
Filed on May 1, 2023, as Appl. No. 18/141,816.
Application 18/141,816 is a continuation of application No. 17/347,187, filed on Jun. 14, 2021, granted, now 12,023,492.
Application 17/347,187 is a continuation of application No. 16/189,655, filed on Nov. 13, 2018, granted, now 11,033,736, issued on Jun. 15, 2021.
Application 16/189,655 is a continuation of application No. 15/096,014, filed on Apr. 11, 2016, granted, now 10,124,166, issued on Nov. 13, 2018.
Application 15/096,014 is a continuation of application No. 14/357,481, granted, now 9,393,409, issued on Jul. 19, 2016, previously published as PCT/US2012/064874, filed on Nov. 13, 2012.
Claims priority of provisional application 61/559,025, filed on Nov. 11, 2011.
Prior Publication US 2023/0271004 A1, Aug. 31, 2023
Int. Cl. A61N 1/36 (2006.01); A61N 1/04 (2006.01)
CPC A61N 1/36003 (2013.01) [A61N 1/0456 (2013.01); A61N 1/36021 (2013.01); A61N 1/36025 (2013.01); A61N 1/36071 (2013.01); A61N 1/36057 (2013.01); A61N 1/36171 (2013.01); A61N 1/36175 (2013.01); A61N 1/36178 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A neuromodulation system comprising:
a processor;
a signal generator communicatively coupled to the processor; and
at least one electrode array communicatively coupled to the signal generator, the at least one electrode array comprising:
a first electrode, and
at least one second electrode,
wherein the processor in cooperation with the signal generator, the first electrode, and the at least one second electrode are configured to deliver a transcutaneous stimulation to a mammal, the transcutaneous stimulation configured by the processor for inducing voluntary movement in the mammal and/or facilitating recovery of autonomic function,
wherein the first electrode is positioned transcutaneously on a spinal cord and/or spinal cord dorsal roots of the mammal,
wherein the at least one second electrode is placed transcutaneously on or over at least one of the spinal cord and/or the spinal cord dorsal roots, a muscle, a nerve, or on or near a target end organ or bodily structure of the mammal, and
wherein the transcutaneous stimulation has a frequency between 1 to 100 Hz and a current between 30 to 200 mA.