| CPC A61M 5/14276 (2013.01) [A61M 5/16809 (2013.01); A61M 2205/02 (2013.01); A61M 2205/3324 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/3553 (2013.01)] | 23 Claims |

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1. An implantable medical device, comprising:
a refillable infusate delivery system, the refillable infusate delivery system comprising a reservoir in fluid communication with an access port;
two or more exterior sensors positioned on an external surface of the implantable medical device and configured to monitor fluid in proximity to an exterior of the implantable medical device for an injection of infusate into a pocket of tissue surrounding the implantable medical device during a procedure to refill the reservoir with infusate when the reservoir is empty; and
a processor configured to monitor the two or more exterior sensors during infusate refill procedures and to activate one or more notification, alert or alarm features to notify a user that a pocket fill may be occurring.
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