US 12,226,561 B2
Magnetic particle separation system with flexible bioprocessing container
Lars Norderhaug, Nesoddtangen (NO); Angel Varela-Rohena, Carlsbad, CA (US); and Nephi D. Jones, Newton, UT (US)
Assigned to Life Technologies Corporation, Carlsbad, CA (US); and Life Technologies AS, Oslo (NO)
Filed by Life Technologies Corporation, Carlsbad, CA (US); and Life Technologies AS, Oslo (NO)
Filed on Feb. 14, 2022, as Appl. No. 17/671,353.
Application 17/671,353 is a division of application No. 16/067,495, granted, now 11,268,056, previously published as PCT/US2016/068067, filed on Dec. 21, 2016.
Claims priority of provisional application 62/272,585, filed on Dec. 29, 2015.
Prior Publication US 2022/0162531 A1, May 26, 2022
Int. Cl. A61M 1/36 (2006.01); B01L 3/00 (2006.01); B03C 1/01 (2006.01); B03C 1/28 (2006.01); B03C 1/30 (2006.01); C07K 16/28 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/26 (2006.01); C12M 3/00 (2006.01)
CPC A61M 1/3618 (2014.02) [B01L 3/505 (2013.01); B03C 1/01 (2013.01); B03C 1/288 (2013.01); B03C 1/30 (2013.01); C12M 1/266 (2013.01); C12M 3/00 (2013.01); C12M 23/14 (2013.01); C12M 23/26 (2013.01); C12M 37/04 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0668 (2013.01); B01L 2400/043 (2013.01); B03C 2201/18 (2013.01); B03C 2201/26 (2013.01); C07K 16/2809 (2013.01); C07K 16/2818 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A magnetic particle separation system, comprising:
a magnetic field generating device, comprising:
an upper surface having a receiving area formed thereon; and
a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface; and
a container assembly disposed on the upper surface, the container assembly comprising:
a flexible container comprising an outer wall having an interior surface that at least partially bounds an internal compartment, the outer wall having a perimeter that encircles the internal compartment, the perimeter including a front side and an opposing back side with the internal compartment being disposed therebetween;
a fluid inlet extending through the outer wall at the front side, the fluid inlet being in fluid communication with the internal compartment;
a fluid outlet extending through the outer wall at the front side, the fluid outlet being in fluid communication with the internal compartment; and
a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet, the first partition being configured such that when a fluid mixture comprising magnetic particles passes from the fluid inlet to the fluid outlet within the internal compartment, the fluid mixture must flow around the first partition.