US 12,226,555 B2
System and method for treating haemorrhagic fluid for autotransfusion
Francis Gadrat, Bordeaux (FR); Benoît Decouture, Nantes (FR); Stéphane Chollet, La Chapelle sur Erdre (FR); Patricia Forest-Villegas, Genas (FR); and Sylvain Picot, Caluire (FR)
Assigned to I-SEP, (FR)
Appl. No. 17/622,482
Filed by I-SEP, Nantes (FR)
PCT Filed Jun. 26, 2020, PCT No. PCT/FR2020/051115
§ 371(c)(1), (2) Date Dec. 23, 2021,
PCT Pub. No. WO2020/260836, PCT Pub. Date Dec. 30, 2020.
Claims priority of application No. 1907004 (FR), filed on Jun. 27, 2019.
Prior Publication US 2022/0241473 A1, Aug. 4, 2022
Int. Cl. A61M 1/02 (2006.01); A61M 1/34 (2006.01)
CPC A61M 1/0281 (2013.01) [A61M 1/0218 (2014.02); A61M 1/342 (2013.01); A61M 2202/0429 (2013.01); A61M 2205/3306 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/7554 (2013.01); A61M 2230/207 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method for treating, by filtration, haemorrhagic fluid contained in a container with a view to subsequent autotransfusion, comprising at least one step of concentration by filtration of said haemorrhagic fluid in order to increase the concentration of red blood cells in the haemorrhagic fluid to reach a target haematocrit level while at the same time removing from the haemorrhagic fluid a filtrate comprising compounds not desired for autotransfusion, characterised in that it further comprises the following steps:
a preliminary step of measuring the haematocrit level of the haemorrhagic fluid; and
a dilution step consisting in adding to the volume of haemorrhagic fluid to be treated a determined volume of dilution fluid, said determined volume of dilution fluid being calculated as a function of the measured haematocrit level of said haemorrhagic fluid and the target haematocrit level;
wherein the treatment is further parameterised to obtain a concentration of compounds not desired for autotransfusion less than a target concentration of compounds not desired for autotransfusion, said target concentration of compounds not desired for autotransfusion also being used to calculate the determined volume of dilution fluid for the dilution step.