	US 12,226,520 B2
	Self-fueled particles for propulsion through flowing aqueous fluids
Christian Kastrup, Vancouver (CA); Ju Hun Yeon, Seoul (KR); James Baylis, Vancouver (CA); and Thomas Frederick Burke, Medford, MA (US)
Assigned to The University of British Columbia, Vancouver (CA); and The General Hospital Corporation, Boston, MA (US)
Filed by The University of British Columbia, Vancouver (CA); and The General Hospital Corporation, Boston, MA (US)
Filed on Mar. 4, 2022, as Appl. No. 17/687,364.
Application 16/295,819 is a division of application No. 15/105,553, granted, now 10,238,598, issued on Mar. 26, 2019, previously published as PCT/CA2014/000721, filed on Oct. 2, 2014.
Application 17/687,364 is a continuation of application No. 16/295,819, filed on Mar. 7, 2019, granted, now 11,266,596.
Claims priority of provisional application 61/916,674, filed on Dec. 16, 2013.
Prior Publication US 2022/0233432 A1, Jul. 28, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/46 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 38/18 (2006.01); A61K 38/48 (2006.01); A61L 15/18 (2006.01); A61L 15/20 (2006.01); A61L 15/42 (2006.01); A61L 15/44 (2006.01); A61L 29/08 (2006.01); A61L 29/10 (2006.01); A61L 29/14 (2006.01); A61L 29/16 (2006.01); A61L 31/08 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); C01F 11/18 (2006.01)

CPC A61K 9/0007 (2013.01) [A61K 9/143 (2013.01); A61K 9/145 (2013.01); A61K 9/1617 (2013.01); A61K 38/18 (2013.01); A61K 38/4833 (2013.01); A61L 15/18 (2013.01); A61L 15/20 (2013.01); A61L 15/425 (2013.01); A61L 15/44 (2013.01); A61L 29/08 (2013.01); A61L 29/10 (2013.01); A61L 29/106 (2013.01); A61L 29/146 (2013.01); A61L 29/16 (2013.01); A61L 31/08 (2013.01); A61L 31/082 (2013.01); A61L 31/088 (2013.01); A61L 31/146 (2013.01); A61L 31/16 (2013.01); C01F 11/18 (2013.01); A61L 2300/254 (2013.01); A61L 2300/418 (2013.01); A61L 2300/606 (2013.01); A61L 2400/04 (2013.01); A61L 2400/12 (2013.01); A61L 2420/06 (2013.01); C01P 2004/61 (2013.01); C01P 2006/16 (2013.01); C12Y 304/21005 (2013.01)]

15 Claims

1. A non-aqueous composition, comprising:

(a) carbonate salt particles; and

(b) an organic acid in solid form, wherein the organic acid is selected from the group consisting of doubly-protonated tranexamic acid (TXA-NH₃⁺), aminocaproic acid, and mixtures thereof;

wherein the carbonate salt particles and organic acid in solid form are present in the composition in the form of a powder or granules in an amount effective to propel the carbonate particles and organic acid in solid form through an aqueous fluid when the non-aqueous composition is introduced to an aqueous fluid.