	US 12,226,500 B2
	Method for suppressing adhesion of air harmful substances
Jia Shi, Sumida-ku (JP); Tomoya Fujii, Sumida-ku (JP); and Hiroyuki Takizawa, Sumida-ku (JP)
Assigned to KAO CORPORATION, Tokyo (JP)
Appl. No. 17/616,455
Filed by KAO CORPORATION, Tokyo (JP)
PCT Filed Jun. 4, 2020, PCT No. PCT/JP2020/022176 § 371(c)(1), (2) Date Dec. 3, 2021, PCT Pub. No. WO2020/246556, PCT Pub. Date Dec. 10, 2020.
Claims priority of application No. 2019-106338 (JP), filed on Jun. 6, 2019; application No. 2019-106339 (JP), filed on Jun. 6, 2019; application No. 2019-106343 (JP), filed on Jun. 6, 2019; and application No. 2019-106344 (JP), filed on Jun. 6, 2019.
Prior Publication US 2022/0249339 A1, Aug. 11, 2022
Int. Cl. A61K 8/19 (2006.01); A61K 8/27 (2006.01); A61K 8/29 (2006.01); A61K 8/31 (2006.01); A61K 8/37 (2006.01); A61K 8/89 (2006.01); A61K 8/891 (2006.01); A61Q 17/00 (2006.01); B82Y 5/00 (2011.01)

CPC A61K 8/27 (2013.01) [A61K 8/29 (2013.01); A61K 8/891 (2013.01); A61Q 17/00 (2013.01); A61K 2800/413 (2013.01); A61K 2800/61 (2013.01); B82Y 5/00 (2013.01)]

17 Claims

1. A method for suppressing adhesion of air harmful substances, the method comprising applying an external preparation to skin to suppress adhesion of air pollutants to the skin, wherein:

the external preparation comprises the following component (AI) and one of components (BI), (BII), or (BIII), and

the ratio by mass of the content of the component (BI), if present, to the content of the component (AI) in the external preparation [(BI)/(AI)] is 9 or less;

the ratio by mass of the content of the component (BII), if present, to the content of the component (AI) in the external preparation [(BII)/(AI)] is 3.5 or less; and

the ratio by mass of the content of the component (BIII), if present, to the content of the component (AI) in the external preparation [(BIII)/(AI)] is 0.85 or less:

Component (AI): a hydrophobized metal oxide having an average primary particle diameter d_AIof 5 nm or more and 700 nm or less,

Component (BI): an ester oil,

Component (BII): a nonvolatile hydrocarbon oil,

Component (BIII): a nonvolatile silicone oil, and

said metal oxide (AI) is applied to said skin in an amount of 0.03 mg/cm²or more and 0.8 mg/cm²or less.