	US 12,226,476 B2
	Helper epitope peptide and application thereof
Wenbing Yao, Jiangsu (CN); Hong Tian, Jiangsu (CN); Yi Xu, Jiangsu (CN); Yu He, Jiangsu (CN); and Xiangdong Gao, Jiangsu (CN)
Assigned to CHINA PHARMACEUTICAL UNIVERSITY, Jiangsu (CN)
Appl. No. 17/052,360
Filed by CHINA PHARMACEUTICAL UNIVERSITY, Jiangsu (CN)
PCT Filed Apr. 19, 2019, PCT No. PCT/CN2019/083484 § 371(c)(1), (2) Date Nov. 2, 2020, PCT Pub. No. WO2019/210782, PCT Pub. Date Nov. 7, 2019.
Claims priority of application No. 201810408586.3 (CN), filed on May 2, 2018.
Prior Publication US 2021/0162041 A1, Jun. 3, 2021
Int. Cl. A61K 39/385 (2006.01); A61K 39/00 (2006.01); C07K 7/08 (2006.01)

CPC A61K 39/385 (2013.01) [A61K 39/0011 (2013.01); C07K 7/08 (2013.01)]

12 Claims

1. A helper epitope peptide consisting of a modified sequence of SEQ ID NO: 1, wherein one or two amino acid residues within SEQ ID NO:1 is 4-nitrophenylalanine, and the modified sequence of SEQ ID NO: 1 is SEQ ID NO: 12.