	US 12,226,473 B2
	SARS-COV-2 antigen polypeptide, recombinant adeno-associated virus expressing the polypeptide, and vaccine containing the virus
Zexin Zhou, Guangdong (CN); Zhongqiu Liu, Guangdong (CN); Guochao Liao, Guangdong (CN); Huapeng Li, Guangdong (CN); Chao Zhang, Guangdong (CN); Xiaoxiao Qi, Guangdong (CN); Junlin Chen, Guangdong (CN); and Deying Yang, Guangdong (CN)
Assigned to Hengda Biomedical Technology Co., Ltd., Guangzhou (CN)
Filed by Hengda Biomedical Technology Co., Ltd., Guangdong (CN)
Filed on May 24, 2021, as Appl. No. 17/327,784.
Application 17/327,784 is a continuation in part of application No. PCT/CN2020/127311, filed on Nov. 7, 2020.
Claims priority of application No. 202010392553.1 (CN), filed on May 11, 2020.
Prior Publication US 2021/0346493 A1, Nov. 11, 2021
Int. Cl. C12N 15/86 (2006.01); A61K 39/12 (2006.01); A61K 39/215 (2006.01); C07K 14/165 (2006.01); C12N 7/00 (2006.01)

CPC A61K 39/215 (2013.01) [C07K 14/165 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C07K 2319/02 (2013.01); C12N 2750/14134 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14151 (2013.01)]

8 Claims

1. An expression vector expressing an SARS-COV-2 antigen polypeptide set forth in SEQ ID NO: 1, comprising an adeno-associated virus inverted terminal repeat sequence, a nucleotide sequence encoding a signal peptide, and a nucleotide sequence encoding the SARS-COV-2 antigen polypeptide.